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Un tercer gui n si acaso el
2019-04-28
Un tercer guión, si acaso el más inquietante de los tres, podría hallarse en la banda de cuatro críticos literarios consagrados mek inhibitors la obra de Archimboldi, el gran autor que Bolaño introduce en la novela 2666. La narración capta una muestra episódica del modo de inserción del intelectual
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While it has been reported that the combination
2019-04-28
While it has been reported that the combination therapy of As2O3 and ATRA is highly effective not only as the front-line treatment [6], but also in relapsed and treatment-refractory APL patients [7], showing fewer adverse events than the combination of ATRA and chemotherapeutic drugs, the efficacy a
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br Introduction Aplastic anemia AA
2019-04-28
Introduction Aplastic anemia (AA) is a rare disease characterized by pancytopenia and a hypocellular bone marrow. Specific cytogenetic abnormalities, monosomy 7 and trisomy 8, are frequently associated with clonal evolution [1]. Clonal cytogenetic abnormalities also may be present with hypocellul
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In primary diagnosis IKZF status
2019-04-28
In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19
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sphingosine The p MAPK pathway activates AP
2019-04-26
The p38 MAPK pathway activates AP1 to regulate transcription of TNF-α [32,33]. Our results show that EC inhibits the expression of total c-Jun and p-c-Jun in the lungs of LPS-challenged mice. This finding suggests that EC may inhibit TNF-α production in the lungs via the p38 MAPK–AP1 signaling pathw
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br Purpose br Methods Participating centers
2019-04-26
Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register
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br Do we need complete isolation of all
2019-04-26
Do we need complete isolation of all PVs in every patient? Circumferential PVI results in satisfactory outcomes for ablation of paroxysmal AF, and electrical isolation of all PVs is currently a standard approach to the treatment of AF, as recommended by the expert consensus statement [6]. Complet
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It is noted that in this study BrS
2019-04-26
It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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La entrega del n mero correspondiente al segundo semestre
2019-04-26
La entrega del número 57, correspondiente al segundo semestre de 2013, ofrece la sección Mirador Latinoamericano, donde se abordan distintos aspectos de la cultura y la literatura en nuestra América. En primer lugar, en el artículo “Crítica literaria y opinión pública: polémicas literarias en Colomb
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Remote monitoring offers ongoing opportunities
2019-04-26
Remote monitoring offers ongoing opportunities for management from three perspectives: Concept of remote monitoring for STF-62247 failure Most HF-related hospitalizations are due to fluid accumulation, and careful surveillance of a patient\'s fluid status and symptoms is important [20]. To eff
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br On Nov every year the International Day for the
2019-04-25
On Nov 25 every year, the International Day for the Elimination of Violence Against Women, and the 16 days of activism that follow it, help to draw the world\'s attention to the scourge of intimate partner violence and other forms of gender-based violence and their harmful effects on women\'s heal
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Hill and colleagues estimate that globally
2019-04-25
Hill and colleagues\' estimate that, globally, about 1·5 million (95% CI 1·2–1·8) children aged 5–14 years died in 2010. This finding is somewhat higher than the total estimated by the UN of 1·3 million, although the UN estimate is within the investigators\' CI. However, their estimate is 87% higher
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En la obra de Cuadra una familia campesina
2019-04-25
En la obra de Cuadra, una familia campesina confronta trágicamente la guerra civil entre conservadores y liberales. Víctimas pasivas de las élites y no actores políticos, estos campesinos ven cómo los principios familiares tradicionales y del minifundio son desarticulados por la guerra y el abuso de
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sphk Este trabajo llama la atenci n sobre dos
2019-04-25
Este trabajo llama la atención sobre dos volúmenes de poesía (, de 1916, y , de 1967) ligados de modo estrecho sphk dos momentos clave de la historia provincial: por un lado, el año del Centenario de la Independencia Nacional —cuya declaración había tenido lugar, como es sabido, en 1816 precisamente
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En el documental Tacos altos en
2019-04-25
En el documental Tacos altos en el barro (Rolando Pardo, 2014), una de las travestis afirma que “somos seres humanos igual que ustedes”, mientras se esparce una crema por su rostro, rodeado de carencias económicas y de infraestructura de todo tipo. Esta cinta se ocupa de la relación entre prostituci
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