• This Ca overload activates the forward mode

  2019-06-05

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

• Sor Juana cuyo genio era para Vigil indudablemente antimonac

  2019-06-05

  

  Sor Juana, cuyo genio era para Vigil indudablemente “antimonacal” —recordemos que estamos en pleno periodo posterior Protease Inhibitor Library las leyes de desamortización de los bienes eclesiásticos— tuvo que tomar una decisión “dictada por las exigencias de su sociedad”, por ello, continúa Vigil,

• The need for better measurement of gender empowerment cannot

  2019-06-05

  

  The need for better measurement of gender empowerment cannot be understated, given that 80% of indicators to monitor SDG5 lack adequate data, often because of an absence of valid measures. Although measures of gender empowerment are available, and more are being developed, there is no consensus on t

• It s finally a year by the end of

  2019-06-05

  

  It\'s finally 2015: a year by the end of which extreme poverty and hunger are to be eradicated, maternal and child mortality are to be drastically reduced, and the trajectory of the global incidence of HIV, tuberculosis, and malaria are to be reversed. Much has been written about where the Millenni

• In Blake Alkire and colleagues now provide additional

  2019-06-05

  

  In , Blake Alkire and colleagues now provide additional measures to help us gain political priority on the public health agendas. In this study, Alkire and colleagues modelled access to surgery in 180 countries on the basis of four criteria: timeliness, surgical capacity, safety, and affordability.

• There is a lot to celebrate and applaud in this

  2019-06-05

  

  There is a lot to celebrate and applaud in this month\'s issue of , but also some sobering findings and a clear demonstration of the need for more research. To start with the positive, Osman Sankoh and fellow INDEPTH Network colleagues announce a new freely accessible repository of Health and Demogr

• Sin embargo las identidades sexuales politizadas no han sido

  2019-06-01

  

  Sin embargo, las identidades sexuales politizadas no han sido simples corolarios de la homofobia y trato despectivo hacia las sexualidades contra culturales. Para hacerse visibles, requirieron complejas condiciones sociales y políticas con el fin de producir un sentido de experiencia de comunidad qu

• For many years international donors philanthropists and char

  2019-06-01

  

  For many years, international donors, philanthropists, and charities have poured money into deworming programmes for children in low-income and middle-income countries in the belief they will contribute to improved health, school performance, and economic development. The Rockefeller Sanitary Commis

• The occurrence of RNRVAS first

  2019-06-01

  

  The occurrence of RNRVAS, first reported as an isolated case in 1985 [16], have since been confirmed in dual-chamber pacemaker recipients undergoing 24-h ambulatory electrocardiograms, who report symptoms similar to those of patients suffering from pacemaker syndrome [17,18]. Incidence of RNRVAS

• pten inhibitor Nademanee et al reported nine symptomatic pat

  2019-06-01

  

  Nademanee et al. reported nine symptomatic patients with BrS who experienced VF and underwent electrophysiological study and catheter ablation [8]. The patients exhibited abnormal epicardial electrograms characterized by fragmented electrograms with a relatively low voltage ( Idiopathic ventricular

• I am delighted to introduce the inaugural

  2019-06-01

  

  I am delighted to introduce the inaugural issue of . It is very likely that you are reading this online, this being an online-only journal, although we have also printed this first issue in order to showcase the journal to readers of . What is certain is that, in accessing this article, and all the

• br Introducci n De una manera

  2019-06-01

  

  Introducción De una manera muy esquemática y ryanodine cost grandes trazos, podemos diferenciar al menos cuatro momentos en los estudios sobre la democracia en América Latina en el último medio siglo, según algunos problemas predominantes. Las limitaciones y quiebres democráticos, las posteriores

• br Unacceptably high rates of adverse outcomes persist

  2019-06-01

  

  Unacceptably high rates of adverse outcomes persist for childbearing women and infants, including maternal and newborn mortality, stillbirth, and short-term and long-term morbidity. In light of the challenges to achieve the UN Sustainable Development Goals, it is timely to reconsider priorities fo

• Since many decades bone tumours have stimulated imagination

  2019-05-31

  

  Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh

• Ro 31-8220 methanesulfonate Our results are consistent with

  2019-05-31

  

  Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].

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