• Introduction Tumor metastases of the skeleton occur in

  2019-04-29

  

  Introduction Tumor metastases of the skeleton occur in up to 80% of patients in progressed stages of cancer, most commonly in cases of breast, lung, prostate, kydney and thyroid tumors [1,2]. Bone metastases are often associated with pathologic fractures, hypercalcemia and spinal cord compression,

• The trabecular bone score TBS is an innovative gray level

  2019-04-29

  

  The trabecular bone score (TBS) is an innovative gray-level texture measurement that utilizes lumbar spine DXA images to discriminate changes in bone microarchitecture [6]. Specifically, TBS measures tridimensional bone areas with different trabecular and microstructural characteristics. TBS has bee

• br Materials and methods br Results

  2019-04-29

  

  Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments We thank all patients and EHop-016 without whom this research would not be possible. JI is the recipient of a National Health and Medical Research Council (NHMRC) and National Heart Foundation

• br Materials and methods br Results We performed immunohisto

  2019-04-28

  

  Materials and methods Results We performed immunohistochemistry for IMP3 on RCC and PC retrieval tissues from patients with bone metastases (Fig. 3). All of the 11 RCC bone metastases samples tested were highly positive (+++) for IMP3, while the non-neoplastic ll-37 within the tumor parenchym

• Furthermore because global food insecurity will be very

  2019-04-28

  

  Furthermore, because global food insecurity will be very expensive to counteract, increased production by the millions of subsistence livestock farmers in the world should be encouraged. At present, yields from their animals are meagre at best, owing to poor nutrition and chronic infections. Unhealt

• br Methods This prospective study was

  2019-04-28

  

  Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befor

• In summary programmed long AVD prolonged

  2019-04-28

  

  In summary, programmed long AVD, prolonged VA conduction time caused by anti-arrhythmic medication, and the rate of ELT (110bpm, below the upper tracking rate of 120bpm) were the reason ELT continued even in the presence of a programmed ELT termination algorithm. Physicians who manage patients with

• The PPI from the CS

  2019-04-28

  

  The PPI from the CS ostium was close to the TCL, suggesting that the CS ostium was on the dominant circuit (Fig. 8B). During entrainment from the CS ostium, the last captured beat of the TA was the second beat after the stimulus, suggesting that the slow conduction area (crosshatch) was located dist

• Case reports br Discussion RV perforation is a rare

  2019-04-28

  

  Case reports Discussion RV perforation is a rare but serious complication of PPM and ICD implantation. It is diagnosed when at least the tip of a passive fixation lead or the screw of an active fixation lead passes through the myocardium and extends into the pericardial cavity [1]. This complica

• However despite the strength of

  2019-04-28

  

  However, despite the strength of the research by Shawar and colleagues, any given process tracing case study can always be improved. In relation to this Article, the empirical tracing of causal processes could be strengthened further in future research, in particular by telling us more explicitly wh

• En las reflexiones sobre la Isla del Encanto de

  2019-04-28

  

  En las reflexiones sobre la “Isla del Encanto” de María Teresa Cortés en su aportación titulada “La configuración de la nación en la narrativa histórica puertorriqueña y el sistema de prácticas ecológicas, siglo ” retoma la labor informativa sobre Puerto Rico, hecha por el funcionario español de ori

• Un tercer gui n si acaso el

  2019-04-28

  

  Un tercer guión, si acaso el más inquietante de los tres, podría hallarse en la banda de cuatro críticos literarios consagrados mek inhibitors la obra de Archimboldi, el gran autor que Bolaño introduce en la novela 2666. La narración capta una muestra episódica del modo de inserción del intelectual

• While it has been reported that the combination

  2019-04-28

  

  While it has been reported that the combination therapy of As2O3 and ATRA is highly effective not only as the front-line treatment [6], but also in relapsed and treatment-refractory APL patients [7], showing fewer adverse events than the combination of ATRA and chemotherapeutic drugs, the efficacy a

• br Introduction Aplastic anemia AA

  2019-04-28

  

  Introduction Aplastic anemia (AA) is a rare disease characterized by pancytopenia and a hypocellular bone marrow. Specific cytogenetic abnormalities, monosomy 7 and trisomy 8, are frequently associated with clonal evolution [1]. Clonal cytogenetic abnormalities also may be present with hypocellul

• In primary diagnosis IKZF status

  2019-04-28

  

  In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19

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