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Salivary amylase activity was not significantly
2024-05-13
Salivary α-amylase activity was not significantly different between bitches with pyometra and healthy bitches, and there were no significant changes after ovariohysterectomy, similar to chromogranin A (Jitpean et al., 2015). Therefore, it is postulated that the SAM axis is not activated in bitches w
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To date the molecular responses of AChE have been partially
2024-05-13
To date, the molecular responses of AChE have been partially analyzed in its mRNA level or protein activity in aquatic animals. To understand the correlation between transcriptional change and activity of AChE, we conducted both experiments in B. koreanus. Generally, the nm to lb patterns of the Bk
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br AChE variants and their functions The AChE gene generates
2024-05-13
AChE variants and their functions The AChE gene generates several splice variants of AChE which are designated as hydrophobic (H), readthrough (R) and tailed (T) forms differing in membrane association and also localisation on a tissue and sub-cellular level. They all undergo significant posttran
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br Materials and methods br Functional demonstrations
2024-05-13
Materials and methods Functional demonstrations of ACh/GABA cotransmission The cotransmission of GABA and ACh has been best characterized in starburst amacrine cells (SACs) of the retina. SACs are a subtype of amacrine cell, a diverse set of retinal interneurons that are crucial for processing
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br Material and methods br Results br Discussion
2024-05-13
Material and methods Results Discussion Clinical gene therapy trials with viral vectors have been in use for treatment of various genetic disorders and diseases, however efficacious, targetable and highly reliable non-viral delivery systems are needed for safe and long-term applications. De
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Oxytocin Since the localization of LO depends on phosphoryla
2024-05-13
Since the localization of 5-LO depends on phosphorylation, we also analyzed the phosphorylation profile of 5-LO-WT and all isoforms by Western blot using specific Oxytocin against the phosphorylation sites S271 and S523. Whereas phosphorylation at S271 activates the 5-LO, inhibits nuclear export an
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The reductase family is composed of
2024-05-13
The 5α-reductase family is composed of three known isozymes, with the types I and II being the most known. Type I isozyme, which is the dominant form, can be found in the skin, liver, kidney, brain and lung. Furthermore, it has been evidenced that type I activity is several times higher in PC than i
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br Materials and methods br Results
2024-05-11
Materials and methods Results Discussion Pulmonary fibrosis is a progressive and chronic lung disease and its typical features include GW441756 sale proliferation, epithelial injury, chronic interstitial inflammation, increased extracellular matrix (ECM) production, and collapse of alveoli,
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Bamboo the fastest growing multipurpose woody plant
2024-05-11
Bamboo, the fastest growing, multipurpose woody plant with a myriad of industrial and domestic uses is intricately associated with the cultural, social and economic conditions of people in many Asian countries. Its uses are not only limited to being used as a substitute for wood in construction, fur
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Platelet derived growth factor PDGF and ciliary neurotrophic
2024-05-11
Platelet-derived growth factor (PDGF) and ciliary neurotrophic factor (CNTF) are expressed by glial pfk and are important to neuron survival and the maintenance of oligodendrocytes. These neurotrophic factors contribute to the remyelination process by increasing the proliferation of oligodendrocyte
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Previous studies have demonstrated that synaptic AMPARs can
2024-05-11
Previous studies have demonstrated that synaptic AMPARs can differ greatly in their mobility; some rapidly and constitutively glycine receptors in and out of the synaptic membrane, while others remain somewhat stable in the synaptic membrane (Luscher et al., 1999, Luthi et al., 1999). We find that
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Activation of AhR is also known to upregulate the expression
2024-05-11
Activation of AhR is also known to upregulate the expression of AhRR (AhR repressor), an inhibitor protein of AhR [29]. However, the exact mechanism by which AhRR represses AhR signaling is not well understood. The initial study by Mimura and colleagues suggested that AhRR is capable of directly com
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br Hypoadiponectinemia in metabolic syndrome APN belongs str
2024-05-11
Hypoadiponectinemia in metabolic syndrome APN belongs structurally to the complement 1q family and is found at high concentrations (>0.01% of total protein) in the serum of healthy individuals [6]. Given the abundance of APN in plasma, it is assumed that alterations in plasma levels of APN might
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CP-809101 hydrochloride mg Adenosine is a ubiquitous homeost
2024-05-11
Adenosine is a ubiquitous homeostatic purine nucleoside that accumulates extracellularly in response to metabolic stresses such as hypoxia and inflammation. Activation of either G protein-coupled adenosine receptors (ARs; A1R, A2AR, A2BR, and A3R) by extracellular adenosine can modulate cell signali
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br Mechanisms of specific immunotherapy Several mechanisms m
2024-05-11
Mechanisms of specific immunotherapy Several mechanisms may be involved in specific immunotherapy of EAMG by active immunization with the therapeutic vaccine in IFA. During the therapy, the therapeutic benefits result from diversion of autoantibody specificities away from pathogenic extracellular
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