• The V V process of the FPGA development includes

  2019-09-26

  

  The V&V process of the FPGA development includes equivalence checking (Huang and Cheng, 1998, Huang et al., 2000, Kuehlmann and Krohm, 1997, Kuehlmann et al., 1995, Burch et al., 1994) as well as the simulation techniques. The equivalence checking can prove that two given designs have the same funct

• hsp70 inhibitor Recent studies show that the

  2019-09-26

  

  Recent studies show that the expression and function of some ion channels such as voltage-gated potassium channels, sodium channels and calcium channels are closely related to the proliferation, migration, and invasion of tumor cells [40], [41], [42]. Firstly, the expression of ion channels is chang

• Endothelins ETs are peptides expressed in

  2019-09-26

  

  Endothelins (ETs) are peptides expressed in both the peripheral and the central nervous systems, which can contribute to sensory changes seen in animal models of inflammatory, cancer and neuropathic pain [10], [11]. All three mammalian isoforms (ET-1, ET-2 and ET-3) activate specific G protein-coupl

• Similarly to other investigations the present

  2019-09-26

  

  Similarly to other investigations, the present study found that ZEA in high concentrations decreases viability of both normal (Liu et al., 2018, Zheng et al., 2018a, Zheng et al., 2018b) and cancer Methylpiperidino pyrazole (Khosrokhavar et al., 2009, Kowalska et al., 2017). The toxic effect of ZEA

• An important focus of the present study has been the

  2019-09-26

  

  An important focus of the present study has been the interaction of HUVECs with extracellular matrix in the regulation of angiogenesis. Matrigel is a gelatinous protein extract secreted by Engelbreth–Holm–Swarm mouse sarcoma cells, and is considered to be a good model of the extracellular matrix (Kl

• NF B is a family of

  2019-09-25

  

  NF-κB is a family of protein mediators that regulate various innate and adaptive immune responses [29,30]. The NF-κB family consists of the following five proteins: c-Rel (Rel); p65 (RelA); RelB; p50(NF-κB1); and p52(NF-κB2). It has been confirmed that NF-κB is activated by TNF family cytokines, suc

• If the effects described here are present in

  2019-09-25

  

  If the effects described here are present in catalysis, their empirical confirmation poses many challenges. Cat state correlations are fragile outside an environment especially suited for their preservation. As present day observational techniques whether in vivo or in vitro were not designed bearin

• Several studies have indicated that ICT induces activation o

  2019-09-25

  

  Several studies have indicated that ICT induces activation of ERK and p38 kinase in a variety of cells. The ERK pathway was involved in and partly contributed to the neuroprotective effects in rat neuronal kasugamycin [14] and anticancer effects in several cancer cells [5], [7], [8]. ICT could also

• br Restenosis after angioplasty remains

  2019-09-25

  

  Restenosis after angioplasty remains a remarkable challenge, although drug-eluting stents have reduced the incidence of restenosis considerably . Vascular smooth muscle Brilliant Blue G clinical (VSMCs) play a pivotal role in the development of intimal thickening and restenosis. VSMCs proliferate

• CFSs are recognized as a driver of

  2019-09-25

  

  CFSs are recognized as a driver of genome instability in human cells and are hotspots for deletions or translocations in cancers (Richards, 2001). The generally accepted model for their expression is that the CFS locus shows a delay in chromatin condensation in early mitosis caused by the persistenc

• To determine whether the same concentration of humic acid

  2019-09-25

  

  To determine whether the same concentration of humic Metabolism Compound Library causes changes in PCR efficiency, we performed another experiment in which the humic acid was added to the PCR mix after bisulfite conversion. All samples that were amplified in the presence of humic acid (thick lines)

• Third DGK protein stabilization by myristic acid is cell

  2019-09-25

  

  Third, DGKδ2 protein stabilization by myristic Dihydroartemisinin is cell line specific. Myristic acid had no obvious effects on DGKδ protein stability in the liver cell line HepG2, pancreas cell line MIA-PaCa-2 and neuronal cell line Neuro-2a cells (Fig. 5). Although myristic acid moderately incre

• br Conclusion br Competing interests br Authors contribution

  2019-09-25

  

  Conclusion Competing interests Authors\' contributions Acknowledgements The work was supported by Aurigene Discovery Technologies (M) Sdn. Bhd., Industrial Doctoral Program sponsorship by Ministry of Higher Education, Malaysia and research grants by the University of Malaya, grant number

• Amyloid Beta-Peptide (1-40) One of the features of

  2019-09-25

  

  One of the features of ROCO proteins, controlled by their domain architecture is their oligomerization status. By size-exclusion chromatography and Western blot analysis, DAPK1 was proved to form homodimers via its GTPase and kinase domains [53]. Similarly, Amyloid Beta-Peptide (1-40) microscopy st

• Epigenetic silencing of genes that determine tumor invasiven

  2019-09-25

  

  Epigenetic silencing of genes that determine tumor invasiveness, growth patterns of tumors, and tumor-cell apoptosis12, 29 may also affect the expression of drug-metabolizing enzymes, thereby providing an additional genetic mechanism in pharmacogenomics. Trisomy 8 that contains wild-type GGH could b

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